11/28/2010 PERMALINK
Gene therapy developed that prevents memory problems in mice with Alzheimer's disease. SOURCE : Scientists at the Gladstone Institute of Neurological Disease in San Francisco have discovered a new strategy to prevent memory deficits in a mouse model of Alzheimer's disease (AD). Humans with AD and mice genetically engineered to simulate the disease have abnormally low levels of an enzyme called EphB2 in memory centers of the brain. Improving EphB2 levels in such mice by gene therapy completely fixed their memory problems.